AAV viral particles
|AAV Adeno-associated viral particles|
PAckGene service information
AAVPrime™ Adeno-associated virus (AAV) products are the ideal tools for inserting genes into a broad range of cell types with high efficiency and enhanced safety. The optimized helper-free human AAV system allows viral packaging without potentially pathogenic helper adenovirus. Many pre-made particle options are available in 14 different serotypes, including fluorescent reporters (Figure 1), or you can have us produce custom AAV particles for you with genes up to 3 kb in length. Particle preparations are available in either standard (for in vitro use only; Figure 1) or purified (suitable for in vivo use; Figure 2) formats.
- High Titers: up to 10^14 GC/ml, total Genome Copies from 5x10^12 GC up to 10^15 GC
- Verstile: usable in a broad range of host cell types.
- Low toxicity: does not integrate into the host genome
- Low immunogenicity: minimal host immune response
- Safe: not associated with any human disease
AAVPrime™ standard AAV particles expressing fluorecent reporters:
AAVPrime™ purified AAV particles expressing eGFP:
Different serotypes differ mainly in surface protein (capsid). Carefully choosing the serotype enables robust gene expression in specific tissues with minimal immune response. Refer to the "Serotypes & Vectors" to learn the essential differences between the different serotypes..
AAV serotypes available (GeneCopoeia) :
Vector choices (GeneCopoeia):
AAV vector collection enables efficient gene expression in a broad range of cell types. For insert lengths up to 3kb.
AAV serotypes available (PackGene) :AAV1 to AAV10, AAV DJ/8, AAV rh10, AAV PHP.eB, PHP.S, 2-retro
Vector choices (PackGene):
up to 22 promoters available for gene overexpression:
Custom shRNA/ miRNA: M serial
Custom sgRNA (CRISPR spCas9, SaCas9/ miRNA: A/B/C serial
Premade AAV particles can be ordered from the list belowScroll down this page for premade AAV particles list
Custom AAV particles production services are currently available for ORF expression:We can deliver AAV particles with titers starting from 10^11 GC/mL or higher depending upon the request. Please follow the procedure hereunder:
1. Identify the gene of interest:Please gather as much as possible of the following information: Gene Description, species, Nucleotide Accession, Entrez Gene ID, Symbols/Aliases or Catalog/product ID. You can also submit a sequence so we can search by target gene sequences homology (BLAST)
2. Choose the vector(s) of interest:Pick-up the vector/expression system(s) you wish to use from the list (see "Vector choices")
3. Send us these informationWe will contact you shortly to confirm: sequences, vectors and controls
833,00 €Premade AAV particles expressing RFP. Serotype: DJ. Promoter: CMV. Learn More
465,00 €Premade AAV particles expressing Gaussia luciferase. Serotype: DJ. Promoter: CMV. Learn More
570,00 €Premade AAV particles expressing Gaussia luciferase. Serotype: DJ. Promoter: CMV. Learn More